Resources

• Reversing Type 2 Diabetes: The Time for Lifestyle Medicine Has Come!

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7400171/

• Low-Carbohydrate Diets in the Management of Obesity and Type 2 Diabetes: A Review from Clinicians Using the Approach in Practice

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177487/

• Reversal of type 2 diabetes: normalisation of beta cell function in association ... The Diabetes Remission Clinical Trial (DiRECT): protocol for a cluster randomise...

https://www.ncbi.nlm.nih.gov/portal/utils/pageresolver.fcgi?recordid=5f4e980ffac7e164f1bcf8e6

• Effects of caloric restriction and weight loss on glycemic control, resistance, and atherosclerotic risk in obese patients with type II diabetes mellitus.

https://www.ncbi.nlm.nih.gov/pubmed/6377892/

• Prolonged caloric restriction in obese patients with type 2 diabetes mellitus decreases myocardial triglyceride content and improves myocardial function.

https://www.ncbi.nlm.nih.gov/pubmed/22282049/

• An intensive weight loss programme in established type 2 diabetes and controls: effects on weight and atherosclerosis risk factors at 1 year.

https://www.ncbi.nlm.nih.gov/pubmed/9472867/

• Year-long weight loss treatment for obese patients with type II diabetes: does including an intermittent very-low-calorie diet improve outcome?

https://www.ncbi.nlm.nih.gov/pubmed/7942937/

• Look AHEAD (Action for Health in Diabetes): design and methods for a clinical trial of weight loss for the prevention of cardiovascular disease in type 2 diabetes.

https://www.ncbi.nlm.nih.gov/pubmed/14500058/

• Association of an intensive lifestyle intervention with remission of type 2 diabetes.

https://www.ncbi.nlm.nih.gov/pubmed/23288372/

• Long-term beneficial effect of a 16-week very low calorie diet on pericardial fat in obese type 2 diabetes mellitus patients.

https://www.ncbi.nlm.nih.gov/pubmed/22282049/

• Durability of a primary care-led weight-management intervention for remission of type 2 diabetes: 2-year results of the DiRECT open-label, cluster-randomised trial.

https://www.ncbi.nlm.nih.gov/pubmed/30852132/

• Piloting a Remission Strategy in Type 2 Diabetes: Results of a Randomized Controlled Trial. Dietetic Treatment in Diabetes Mellitus.

https://www.ncbi.nlm.nih.gov/pubmed/6754302/

• Examination of current dietary recommendations for individuals with diabetes mellitus. Review New perspectives in nutrition management of diabetes mellitus.

https://www.ncbi.nlm.nih.gov/pubmed/21656330/

• Management of Hyperglycemia in Type 2 Diabetes, 2018. A Consensus Report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD).

https://www.ncbi.nlm.nih.gov/pubmed/30291106/

• Review Low-carbohydrate nutrition and metabolism.

https://www.ncbi.nlm.nih.gov/pubmed/17684196/

• Diabetes Remission after Nonsurgical Intensive Lifestyle Intervention in Obese Patients with Type 2 Diabetes.

https://www.ncbi.nlm.nih.gov/pubmed/26114120/

• Remission of recently diagnosed type 2 diabetes mellitus with weight loss and exercise. Effect of a Low-Calorie Diet on Restoration of Normoglycemia in Obese subjects with Type 2 Diabetes.

https://www.ncbi.nlm.nih.gov/pubmed/25636149/

• Reversal of type 2 diabetes: normalisation of beta cell function in association with decreased pancreas and liver triacylglycerol.

https://www.ncbi.nlm.nih.gov/pubmed/21656330/

• Very Low-Calorie Diet and 6 Months of Weight Stability in Type 2 Diabetes: Pathophysiological Changes in Responders and Nonresponders.

https://www.ncbi.nlm.nih.gov/pubmed/27002059/

• Primary care-led weight management for remission of type 2 diabetes (DiRECT): an open-label, cluster-randomised trial.

https://www.ncbi.nlm.nih.gov/pubmed/29221645/

• The effects of low-carbohydrate versus conventional weight loss diets in severely obese adults: one- year follow-up of a randomized trial.

https://www.ncbi.nlm.nih.gov/pubmed/15148064/

• Beneficial effect of low carbohydrate in low calorie diets on visceral fat reduction in type 2 diabetic patients with obesity.

https://www.ncbi.nlm.nih.gov/pubmed/15331203/

• Beneficial effects of a Paleolithic diet on cardiovascular risk factors in type 2 diabetes: a randomized cross-over pilot study.

https://www.ncbi.nlm.nih.gov/pubmed/19604407/

• Comparative study of the effects of a 1-year dietary intervention of a low-carbohydrate diet versus a low-fat diet on weight and glycemic control in type 2 diabetes.

https://www.ncbi.nlm.nih.gov/pubmed/19366978/

• Short-term effects of severe dietary carbohydrate-restriction advice in Type 2 diabetes--a randomized controlled trial.

https://www.ncbi.nlm.nih.gov/pubmed/16409560/

• A low-carbohydrate diet is more effective in reducing body weight than healthy eating in both diabetic and non-diabetic subjects.

https://www.ncbi.nlm.nih.gov/pubmed/17971178/

• The Canadian Trial of Carbohydrates in Diabetes (CCD), a 1-y controlled trial of low-glycemic-index dietary carbohydrate in type 2 diabetes: no effect on glycated haemoglobin but reduction in C- reactive protein.

https://www.ncbi.nlm.nih.gov/pubmed/18175744/

• The effect of a low-carbohydrate, ketogenic diet versus a low-glycemic index diet on glycemic control in type 2 diabetes mellitus.

https://www.ncbi.nlm.nih.gov/pubmed/19099589/

• An Online Intervention Comparing a Very Low-Carbohydrate Ketogenic Diet and Lifestyle Recommendations Versus a Plate Method Diet in Overweight Individuals with Type 2 Diabetes: A Randomized Controlled Trial.

https://www.ncbi.nlm.nih.gov/pubmed/28193599/

• Twelve-month outcomes of a randomized trial of a moderate-carbohydrate versus very low- carbohydrate diet in overweight adults with type 2 diabetes mellitus or prediabetes.

https://www.ncbi.nlm.nih.gov/pubmed/29269731/

• The effects of low-carbohydrate versus conventional weight loss diets in severely obese adults: one- year follow-up of a randomized trial.

https://www.ncbi.nlm.nih.gov/pubmed/15767618/

• Effect of a low-carbohydrate diet on appetite, blood glucose levels, and resistance in obese patients with type 2 diabetes.

https://www.ncbi.nlm.nih.gov/pubmed/15767618/

• Effectiveness and Safety of a Novel Care Model for the Management of Type 2 Diabetes at 1 Year: An Open-Label, Non-Randomized, Controlled Study.

https://www.ncbi.nlm.nih.gov/pubmed/29417495/

• Cardiovascular disease risk factor responses to a type 2 diabetes care model including nutritional ketosis induced by sustained carbohydrate restriction at 1 year: an open label, non-randomized, controlled study.

https://www.ncbi.nlm.nih.gov/pubmed/29712560/

• Weight loss with a low-carbohydrate, Mediterranean, or low-fat diet.

https://www.ncbi.nlm.nih.gov/pubmed/18635428/

• Association of an intensive lifestyle intervention with remission of type 2 diabetes.

https://www.ncbi.nlm.nih.gov/pubmed/23288372/

• Primary care-led weight management for remission of type 2 diabetes (DiRECT): an open-label, cluster-randomised trial.

https://www.ncbi.nlm.nih.gov/pubmed/29221645/

• Durability of a primary care-led weight-management intervention for remission of type 2 diabetes: 2-year results of the DiRECT open-label, cluster-randomised trial.

https://www.ncbi.nlm.nih.gov/pubmed/30852132/

• A randomized trial comparing a very low carbohydrate diet and a calorie-restricted low fat diet on body weight and cardiovascular risk factors in healthy women.

https://www.ncbi.nlm.nih.gov/pubmed/12679447/

• Review Effects of low-carbohydrate vs low-fat diets on weight loss and cardiovascular risk factors: a meta-analysis of randomized controlled trials.

https://www.ncbi.nlm.nih.gov/pubmed/16476868/

• Twelve-month outcomes of a randomized trial of a moderate-carbohydrate versus very low- carbohydrate diet in overweight adults with type 2 diabetes mellitus or prediabetes.

https://www.ncbi.nlm.nih.gov/pubmed/29269731/

• Short-term safety, tolerability and efficacy of a very low-calorie-ketogenic diet interventional weight loss program versus hypocaloric diet in patients with type 2 diabetes mellitus.

https://www.ncbi.nlm.nih.gov/pubmed/27643725/

• Effectiveness and Safety of a Novel Care Model for the Management of Type 2 Diabetes at 1 Year: An Open-Label, Non-Randomized, Controlled Study.

https://www.ncbi.nlm.nih.gov/pubmed/29417495/

• Effect of low-calorie versus low-carbohydrate ketogenic diet in type 2 diabetes.

https://www.ncbi.nlm.nih.gov/pubmed/22673594/

• A non-calorie-restricted low-carbohydrate diet is effective as an alternative therapy for patients with type 2 diabetes.

https://www.ncbi.nlm.nih.gov/pubmed/24390522/

• Effect of 6-month adherence to a very low carbohydrate diet program.

https://www.ncbi.nlm.nih.gov/pubmed/12106620/

• The metabolic response to a high-protein, low-carbohydrate diet in men with type 2 diabetes mellitus.

https://www.ncbi.nlm.nih.gov/pubmed/16423633/

• Improvements in glucose metabolism and sensitivity with a low-carbohydrate diet in obese patients with type 2 diabetes.

https://www.ncbi.nlm.nih.gov/pubmed/24015695/

• Durability of a primary care-led weight-management intervention for remission of type 2 diabetes: 2-year results of the DiRECT open-label, cluster-randomised trial.

https://www.ncbi.nlm.nih.gov/pubmed/30852132/